The half-life of caffeine can be used to calculate how long coffee will affect you after you drink some. Knowing this can help you adjust your coffee intake in order to improve your sleep schedule, or help you determine how often you should drink caffeine in order to maintain a stable level of caffeine through the day.

The biological half-life of caffeine in typical adults is between 5 to 6 hours. This means if you had 100 grams of caffeine, you would have around 50 grams after 5 hours.

Keep in mind that after the amount becomes very small, it is likely that the body will dispose of it all at once rather than halving the amount forever.